Cellular Biochemistry

Sean Crosson - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems

Glyn Dawson - ProfessorLipid signalling pathways and progrd cell death in brain and tumors; inherited lysosomal storage diseases.

Herbert C Friedmann - Associate ProfessorBacterial enzymes; nucleotide, porphyrin, bile pigment, and corrinoid metabolism; bacterial delta-aminolevulinic acid synthesis and control.

Eugene Goldwasser - ProfessorBiochemistry of blood cell differentiation; mode of action of erythropoietin.

Geoffrey L Greene - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.

Robert Haselkorn - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans.

Robert J Keenan - Assistant ProfessorStructural biology and directed evolution.

David Kovar - Assistant ProfessorMolecular mechanisms of actin assembly in fission yeast: molecular genetic to in vitro single filament studies.

Shutsung Liao - ProfessorSex hormone action; mechanism of cancer progression and suppression; modulation of cholesterol, molecular aaction of herbal medicine.

Tao Pan - Associate ProfessorRNA genomics, RNA epigenetics, RNA folding

Ronald S Rock - Assistant ProfessorMolecular motors; cytoskeletal organization; single-molecule biophysics

Bernard Roizman - ProfessorHerpes simplex viruses, gene function and regulation, mechanisms of latent infection, vectors for gene therapy.

Angelo M Scanu - ProfessorGenetic mechanisms in dyslipoproteinemias in humans; metalloproteinases and kringle-containing proteins; proteoglycans in atherogenesis.

Nancy B Schwartz - ProfessorTranscriptional control of ECM expression during chondrogenesis and neurogenesis; regulation of sulfate activation; skeletal dysplasias.

Theodore L Steck - ProfessorMembrane cholesterol biochemistry and cholesterol homeostasis.

Donald F Steiner - ProfessorBiosynthesis and evolution of pancreatic islet hormones; protein precursor processing mechanisms; development and function of the islet alpha (glucagon) and beta (insulin) cells.
Chemical Biology

Sean Crosson - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems

Geoffrey L Greene - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.

Robert J Keenan - Assistant ProfessorStructural biology and directed evolution.

Stephen B.H. Kent - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.

Anthony A Kossiakoff - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.

Marvin W Makinen - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.

Joseph A Piccirilli - Associate ProfessorChemistry/biochemistry of nucleic acids; structure and mechanism of ribozymes (catalytic RNA); bioorganic chemistry.

Ronald S Rock - Assistant ProfessorMolecular motors; cytoskeletal organization; single-molecule biophysics

Benoit Roux - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.
DNA Repair and Recombination

Phoebe A Rice - Associate ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.

James A Shapiro - ProfessorGenome reorganization and multicellular regulatory systems in bacteria populations.
Molecular and Membrane Biophysics

Erin J Adams - Assistant ProfessorStructure and biochemistry of proteins involved in immunological recognition. Characterization of gamma delta T cell receptors and their ligands and activating and inhibitory receptors involved in the innate immune response.

Francisco Bezanilla - ProfessorBiophysics and dynamics of ion channels

Sean Crosson - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems

Godfrey S Getz - ProfessorStructure and function of apolipoproteins in lipoprotein assembly, and in atherosclerosis and Alzheimers disease pathogenesis.

Stephen B.H. Kent - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.

Shohei Koide - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.

Anthony A Kossiakoff - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.

David Kovar - Assistant ProfessorMolecular mechanisms of actin assembly in fission yeast: molecular genetic to in vitro single filament studies.

Marvin W Makinen - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.

Stephen C Meredith - Associate ProfessorLipid-protein interactions; lipoprotein structure; surface phenomena in biology.

Keith Moffat - ProfessorSynchrotron radiation; time-resolved macromolecular crystallography; light-sensitive proteins

Tao Pan - Associate ProfessorRNA genomics, RNA epigenetics, RNA folding

Eduardo Perozo - ProfessorStructure and Dynamics of Ion Channels and transporters

Joseph A Piccirilli - Associate ProfessorChemistry/biochemistry of nucleic acids; structure and mechanism of ribozymes (catalytic RNA); bioorganic chemistry.

Phoebe A Rice - Associate ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.

Ronald S Rock - Assistant ProfessorMolecular motors; cytoskeletal organization; single-molecule biophysics

Benoit Roux - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.

Tobin R Sosnick - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.

Edwin W Taylor - ProfessorMolecular mechanism of muscle contraction, nonmuscle actomyosin, cell motility, microfilaments, and microtubules
Nucleic Acid Biochemistry

Robert Haselkorn - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans.

Tao Pan - Associate ProfessorRNA genomics, RNA epigenetics, RNA folding

Phoebe A Rice - Associate ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.

Bernard Roizman - ProfessorHerpes simplex viruses, gene function and regulation, mechanisms of latent infection, vectors for gene therapy.

Tobin R Sosnick - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.

Ira G Wool - ProfessorStructure and function of eukaryotic ribosomes; RNA structures; RNA-protein interaction.
Protein Engineering Folding and Design

Francisco Bezanilla - ProfessorBiophysics and dynamics of ion channels

Godfrey S Getz - ProfessorStructure and function of apolipoproteins in lipoprotein assembly, and in atherosclerosis and Alzheimers disease pathogenesis.

Geoffrey L Greene - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.

Robert J Keenan - Assistant ProfessorStructural biology and directed evolution.

Stephen B.H. Kent - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.

Shohei Koide - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.

Anthony A Kossiakoff - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.

Marvin W Makinen - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.

Stephen C Meredith - Associate ProfessorLipid-protein interactions; lipoprotein structure; surface phenomena in biology.

Keith Moffat - ProfessorSynchrotron radiation; time-resolved macromolecular crystallography; light-sensitive proteins

Eduardo Perozo - ProfessorStructure and Dynamics of Ion Channels and transporters

Ronald S Rock - Assistant ProfessorMolecular motors; cytoskeletal organization; single-molecule biophysics

Benoit Roux - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.

Tobin R Sosnick - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.
Structural and Computational Biology

Erin J Adams - Assistant ProfessorStructure and biochemistry of proteins involved in immunological recognition. Characterization of gamma delta T cell receptors and their ligands and activating and inhibitory receptors involved in the innate immune response.

Sean Crosson - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems

Geoffrey L Greene - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.

Robert J Keenan - Assistant ProfessorStructural biology and directed evolution.

Stephen B.H. Kent - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.

Shohei Koide - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.

Anthony A Kossiakoff - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.

Marvin W Makinen - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.

Keith Moffat - ProfessorSynchrotron radiation; time-resolved macromolecular crystallography; light-sensitive proteins

Eduardo Perozo - ProfessorStructure and Dynamics of Ion Channels and transporters

Phoebe A Rice - Associate ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.

Benoit Roux - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.

Tobin R Sosnick - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.